Poster. 17th Congress Int Gynecologic Cancer Society, Kyoto, Japon, sept 2018

poster flabra Kyoto 005

Burden of Disease, Early Diagnosis, and Treatment of Merkel Cell Carcinoma in Latin America

Trabajo presentado por la Autora de nuestro Instituto Dra Gabriela Cinat

Link para ver el trabajo :

 Cinat 2018

Analysis of tumoral spheres growing in a multichamber microfluidic device.

Belgorosky D, Fernández-Cabada T, Peñaherrera-Pazmiño AB, Langle Y, Booth R, Bhansali S, Pérez MS, Eiján AM, Lerner B.

J Cell Physiol. 2018 Sep;233(9):6327-6336. doi: 10.1002/jcp.26519. Epub 2018 Mar 25

 

 

 

 

 

E-poster presentado en el XXIII Congreso Argentino de Hematología en noviembre 2017 “Linfoma de Hodgkin clásico de reciente diagnóstico: experiencia en una institución.

Ver: MelilloL-P-190(345) 2

Flavonoid Silybin improves the response to radiotherapy in invasive bladder cancer.

Cormick BPM, Langle Y, Belgorosky D, Vanzulli S, Balarino N, Sandes E, Eiján AM.

J Cell Biochem. 2018 Jan 24. doi: 10.1002/jcb.26693. [Epub ahead of print]

 

https://www.ncbi.nlm.nih.gov/pubmed/29363820

Bacillus Calmette-Guerin improves local and systemic response to radiotherapy in invasive bladder cancer.

Prack Mc Cormick B, Belgorosky D, Langle Y, Balarino N, Sandes E, Eiján AM.

Nitric Oxide. 2017 Apr 1;64:22-30. doi: 10.1016/j.niox.2017.01.008. Epub 2017 Jan 23.

 

https://www.ncbi.nlm.nih.gov/pubmed/28126499

FGFR3 Down-Regulation is Involved in bacillus Calmette-Guérin Induced Bladder Tumor Growth Inhibition.

Langle YV, Belgorosky D, Prack McCormick B, Sahores A, Góngora A, Baldi A, Lanari C, Lamb C, Eiján AM.

J Urol. 2016 Jan;195(1):188-97. doi: 10.1016/j.juro.2015.06.093. Epub 2015 Jul 2.

https://www.ncbi.nlm.nih.gov/pubmed/26144336Breast cancer stem cells are involved in Trastuzumab resistance through the HER2 modulation in 3D culture.

Rodríguez CE, Berardi DE, Abrigo M, Todaro LB, Bal de Kier Joffé ED, Fiszman GL.

J Cell Biochem. 2018 Feb;119(2):1381-1391. doi: 10.1002/jcb.26298. Epub 2017 Sep 25.

https://www.ncbi.nlm.nih.gov/pubmed/28722778

PKCδ Inhibition Impairs Mammary Cancer Proliferative Capacity But Selects Cancer Stem Cells, Involving Autophagy.

Berardi DE, Flumian C, Rodriguez CE, Bessone MI, Cirigliano SM, Joffé ED, Fiszman GL, Urtreger AJ, Todaro LB.

J Cell Biochem. 2016 Mar;117(3):730-40. doi: 10.1002/jcb.25358. Epub 2015 Sep 10.

https://www.ncbi.nlm.nih.gov/pubmed/26335446


High RAC3 expression levels are required for induction and maintaining of cancer cell stemness.

Panelo LC, Machado MS, Rubio MF, Jaworski F, Alvarado CV, Paz LA, Urtreger AJ, Vazquez E, Costas MA.

Oncotarget. 2017 Dec 22;9(5):5848-5860. doi: 10.18632/oncotarget.23635. eCollection 2018 Jan 19.

https://www.ncbi.nlm.nih.gov/pubmed/29464039

CIGB-300, an anti-CK2 peptide, inhibits angiogenesis, tumor cell invasion and metastasis in lung cancer models.

Benavent Acero F, Capobianco CS, Garona J, Cirigliano SM, Perera Y, Urtreger AJ, Perea SE, Alonso DF, Farina HG.

Lung Cancer. 2017 May;107:14-21. doi: 10.1016/j.lungcan.2016.05.026. Epub 2016 Jun 1.

https://www.ncbi.nlm.nih.gov/pubmed/27319334

The synthetic peptide CIGB-300 modulates CK2-dependent signaling pathways affecting the survival and chemoresistance of non-small cell lung cancer cell lines.

Cirigliano SM, Díaz Bessone MI, Berardi DE, Flumian C, Bal de Kier Joffé ED, Perea SE, Farina HG, Todaro LB, Urtreger AJ.

Cancer Cell Int. 2017 Mar 31;17:42. doi: 10.1186/s12935-017-0413-y. eCollection 2017.

https://www.ncbi.nlm.nih.gov/pubmed/28373828

P2.05: The Synthetic Peptide CIGB-300 Inhibits NF-κB Translocation Affecting the Survival and Chemoresistance of NSCLC Cell Lines: Track: Biology and Pathogenesis.

Cirigliano S, Díaz Bessone MI, Flumian C, Berardi D, Perea S, De Kier Joffé EB, Farina H, Todaro L, Urtreger A.

J Thorac Oncol. 2016 Oct;11(10S):S218-S219. doi: 10.1016/j.jtho.2016.08.079. Epub 2016 Sep 22. No abstract available.

https://www.ncbi.nlm.nih.gov/pubmed/27676542

Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis.

Venturutti L, Romero LV, Urtreger AJ, Chervo MF, Cordo Russo RI, Mercogliano MF, Inurrigarro G, Pereyra MG, Proietti CJ, Izzo F, Díaz Flaqué MC, Sundblad V, Roa JC, Guzmán P, Bal de Kier Joffé ED, Charreau EH, Schillaci R, Elizalde PV.

Oncogene. 2016 Apr 28;35(17):2208-22. doi: 10.1038/onc.2015.281. Epub 2015 Jul 27.

https://www.ncbi.nlm.nih.gov/pubmed/26212010

PKCδ Inhibition Impairs Mammary Cancer Proliferative Capacity But Selects Cancer Stem Cells, Involving Autophagy.

Berardi DE, Flumian C, Rodriguez CE, Bessone MI, Cirigliano SM, Joffé ED, Fiszman GL, UrtregerAJ, Todaro LB.

J Cell Biochem. 2016 Mar;117(3):730-40. doi: 10.1002/jcb.25358. Epub 2015 Sep 10.

https://www.ncbi.nlm.nih.gov/pubmed/26335446

Pharmacological Approaches in an Experimental Model of Non-Small Cell Lung Cancer: Effects on Tumor Biology.

Mateu-Jimenez M, Fermoselle C, Rojo F, Mateu J, Peña R, Urtreger AJ, Diament MJ, Joffé ED, Pijuan L, Herreros AG, Barreiro E.

Curr Pharm Des. 2016;22(34):5300-5310.

https://www.ncbi.nlm.nih.gov/pubmed/27339432

In Vitro Antitumor Effects of AHR Ligands Aminoflavone (AFP 464) and Benzothiazole (5F 203) in Human Renal Carcinoma Cells.

Luzzani GA, Callero MA, Kuruppu AI, Trapani V, Flumian C, Todaro L, Bradshaw TD, Loaiza Perez AI.

J Cell Biochem. 2017 Dec;118(12):4526-4535. doi: 10.1002/jcb.26114. Epub 2017 Jun 12.

https://www.ncbi.nlm.nih.gov/pubmed/28471540

Laminin Modulates the Stem Cell Population in LM05-E Murine Breast Cancer Cells through the Activation of the MAPK/ERK Pathway.

Berardi DE, Raffo D, Todaro LB, Simian M.

Cancer Res Treat. 2017 Oct;49(4):869-879. doi: 10.4143/crt.2016.378. Epub 2016 Dec 6.

https://www.ncbi.nlm.nih.gov/pubmed/28052658

AhR ligand Aminoflavone inhibits α6-integrin expression and breast cancer sphere-initiating capacity.

Brantley E, Callero MA, Berardi DE, Campbell P, Rowland L, Zylstra D, Amis L, Yee M, Simian M, Todaro L, Loaiza-Perez AI, Soto U.

Cancer Lett. 2016 Jun 28;376(1):53-61. doi: 10.1016/j.canlet.2016.03.025. Epub 2016 Mar 17.

https://www.ncbi.nlm.nih.gov/pubmed/26996297

CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs.

De Luca P, Dalton GN, Scalise GD, Moiola CP, Porretti J, Massillo C, Kordon E, Gardner K, Zalazar F, Flumian C, Todaro L, Vazquez ES, Meiss R, De Siervi A.

Oncotarget. 2016 Apr 5;7(14):18798-811. doi: 10.18632/oncotarget.7711.

https://www.ncbi.nlm.nih.gov/pubmed/26933806N4 -aryl substituted thiosemicarbazones derived from 1-indanones as potential anti-tumor agents for breast cancer treatment.

Sólimo A, Soraires Santacruz MC, Loaiza Perez AI, Bal de Kier Joffé E, Finkielsztein LM, Callero MA.

J Cell Physiol. 2018 Jun;233(6):4677-4687. doi: 10.1002/jcp.26240. Epub 2018 Jan 4.

https://www.ncbi.nlm.nih.gov/pubmed/29111571

The Immune System As a New Possible Cell Target for AFP 464 in a Spontaneous Mammary Cancer Mouse Model.

Callero MA, Rodriguez CE, Sólimo A, Bal de Kier Joffé E, Loaiza Perez AI.

J Cell Biochem. 2017 Sep;118(9):2841-2849. doi: 10.1002/jcb.25934. Epub 2017 Apr 27.

https://www.ncbi.nlm.nih.gov/pubmed/28206673

Therapeutic potential of bleomycin plus suicide or interferon-β gene transfer combination for spontaneous feline and canine melanoma.

Agnetti L, Fondello C, Villaverde MS, Glikin GC, Finocchiaro LME.

Oncoscience. 2017 Dec 28;4(11-12):199-214. doi: 10.18632/oncoscience.387. eCollection 2017 Nov.

https://www.ncbi.nlm.nih.gov/pubmed/29344558

Inhibition of bioenergetic metabolism by the combination of metformin and 2-deoxyglucose highly decreases viability of feline mammary carcinoma cells.

Arbe MF, Fondello C, Agnetti L, Álvarez GM, Tellado MN, Glikin GC, Finocchiaro LME, Villaverde MS.

Res Vet Sci. 2017 Oct;114:461-468. doi: 10.1016/j.rvsc.2017.07.035. Epub 2017 Aug 3.

https://www.ncbi.nlm.nih.gov/pubmed/28802138

Recent clinical trials of cancer immunogene therapy in companion animals.

Finocchiaro LME, Glikin GC.

World J Exp Med. 2017 May 20;7(2):42-48. doi: 10.5493/wjem.v7.i2.42. eCollection 2017 May 20. Review.

https://www.ncbi.nlm.nih.gov/pubmed/28589078

Bortezomib Enhances the Antitumor Effects of Interferon-β Gene Transfer on Melanoma Cells.

Rossi UA, Finocchiaro LME, Glikin GC.

Anticancer Agents Med Chem. 2017;17(5):754-761. doi: 10.2174/1871520616666160923103849.

https://www.ncbi.nlm.nih.gov/pubmed/27677689

Interferon-β gene transfer inhibits melanoma cells adhesion and migration.

Rossi ÚA, Finocchiaro LM, Glikin GC.

Cytokine. 2017 Jan;89:201-208. doi: 10.1016/j.cyto.2015.11.012. Epub 2015 Dec 1.

https://www.ncbi.nlm.nih.gov/pubmed/26597133

The combination of bleomycin with suicide or interferon-β gene transfer is able to efficiently eliminate human melanoma tumor initiating cells.

Fondello C, Agnetti L, Villaverde MS, Simian M, Glikin GC, Finocchiaro LME.

Biomed Pharmacother. 2016 Oct;83:290-301. doi: 10.1016/j.biopha.2016.06.038. Epub 2016 Jul 8.

https://www.ncbi.nlm.nih.gov/pubmed/27399807

Cytotoxic effects induced by interferon-ω gene lipofection through ROS generation and mitochondrial membrane potential disruption in feline mammary carcinoma cells.

Villaverde MS, Targovnik AM, Miranda MV, Finocchiaro LM, Glikin GC.

Cytokine. 2016 Aug;84:47-55. doi: 10.1016/j.cyto.2016.05.018. Epub 2016 May 26.

https://www.ncbi.nlm.nih.gov/pubmed/27236354

Genomic analysis of head and neck cancer cases from two high incidence regions.

Perdomo S, Anantharaman D, Foll M, Abedi-Ardekani B, Durand G, Reis Rosa LA, Holmila R, Le Calvez-Kelm F, Tajara EH, Wünsch-Filho V, Levi JE, Vilensky M, Polesel J, Holcatova I, Simonato L, Canova C, Lagiou P, McKay JD, Brennan P.

PLoS One. 2018 Jan 29;13(1):e0191701. doi: 10.1371/journal.pone.0191701. eCollection 2018.

 

Circulating tumor DNA detection in head and neck cancer: evaluation of two different detection approaches.

Perdomo S, Avogbe PH, Foll M, Abedi-Ardekani B, Facciolla VL, Anantharaman D, Chopard P, Calvez-Kelm FL, Vilensky M, Polesel J, Holcatova I, Simonato L, Canova C, Lagiou P, McKay JD, Brennan P.

Oncotarget. 2017 Aug 7;8(42):72621-72632. doi: 10.18632/oncotarget.20004. eCollection 2017 Sep 22.

 

Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.

Lesseur C, Diergaarde B, Olshan AF, Wünsch-Filho V, Ness AR, Liu G, Lacko M, Eluf-Neto J, Franceschi S, Lagiou P, Macfarlane GJ, Richiardi L, Boccia S, Polesel J, Kjaerheim K, Zaridze D,